3D Printed Anchoring Sutures for Permanent Shaping of Tissues.

ABSTRACT: Sutures are one of the most widely used devices for adhering separated tissues after injury or surgery. However, most sutures require knotting, which can create a risk of inflammation, and can act as mechanically weak points that often result in breakage and slipping. Here, an anchoring suture is presented with a design that facilitates its propagation parallel to the suturing direction, while maximizing its resistive force against the opposite direction of external force to lock its position in tissues. Different microstructures of suture anchors are systematically designed using orthogonal arrays, and selected based on shape factors associated with mechanical strength. 3D printing is used to fabricate different types of hollow microstructured suture anchors, and optimize their structure

SUBMITTER: Wei W 

PROVIDER: S-EPMC5932114 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature