Effect of Frequent Dialysis on Renal Recovery: Results From the Acute Renal Failure Trial Network Study.

ABSTRACT:

Introduction

The optimal frequency of intermittent hemodialysis (IHD) in the treatment of acute kidney injury (AKI) remains unclear. Increasing the frequency of IHD, while offering the possible advantage of reduced ultrafiltration requirement and less hemodynamic instability per session, amplifies patient contact with an extracorporeal circuit with possible deleterious cardiovascular and immunological consequences. A recent study suggested that intensive renal replacement therapy (RRT) is associated with a decrease in urine output during AKI. We hypothesized that increased frequency of IHD may be associated with delayed renal recovery.

Methods

This is a post hoc analysis of the Acute Renal Failure Trial Network (ATN) study. The ATN study was a large randomized multice

SUBMITTER: Vijayan A 

PROVIDER: S-EPMC5932307 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature