The Prevalence of Phenylketonuria in Arab Countries, Turkey, and Iran: A Systematic Review.

ABSTRACT:

Background/objectives

This paper seeks to identify the prevalence of Phenylketonuria (PKU) in Arab countries, Turkey, and Iran. The study reviewed the existence of comprehensive national newborn screening programs and reported consanguinity rates.

Methods

A computer based literature search was conducted using relevant keywords to retrieve studies conducted on PKU. A total of 34 articles were included. Prevalence was categorized based on the type of screening method used for PKU diagnoses.

Results

The prevalence of classical PKU diagnosed through a comprehensive national newborn screening program ranged from 0.005% to 0.0167%. The highest prevalence was reported in Turkey at 0.0167%, whereas the lowest prevalence was reported in the UAE, 0.005%.

Conclusion

The f

SUBMITTER: El-Metwally A 

PROVIDER: S-EPMC5932526 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature