The combined effect of mammographic texture and density on breast cancer risk: a cohort study.

ABSTRACT: BACKGROUND:Texture patterns have been shown to improve breast cancer risk segregation in addition to area-based mammographic density. The additional value of texture pattern scores on top of volumetric mammographic density measures in a large screening cohort has never been studied. METHODS:Volumetric mammographic density and texture pattern scores were assessed automatically for the first available digital mammography (DM) screening examination of 51,400 women (50-75 years of age) participating in the Dutch biennial breast cancer screening program between 2003 and 2011. The texture assessment method was developed in a previous study and validated in the current study. Breast cancer information was obtained from the screening registration system and through linkage with the Netherlands Can

SUBMITTER: Wanders JOP 

PROVIDER: S-EPMC5932877 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature