FluxPyt: a Python-based free and open-source software for 13C-metabolic flux analyses.

ABSTRACT: 13C-Metabolic flux analysis (MFA) is a powerful approach to estimate intracellular reaction rates which could be used in strain analysis and design. Processing and analysis of labeling data for calculation of fluxes and associated statistics is an essential part of MFA. However, various software currently available for data analysis employ proprietary platforms and thus limit accessibility. We developed FluxPyt, a Python-based truly open-source software package for conducting stationary 13C-MFA data analysis. The software is based on the efficient elementary metabolite unit framework. The standard deviations in the calculated fluxes are estimated using the Monte-Carlo analysis. FluxPyt also automatically creates flux maps based on a template for visualization of the MFA results. The flux d

SUBMITTER: Desai TS 

PROVIDER: S-EPMC5933345 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature