Broader autism phenotype in parents of children with autism: a systematic review of percentage estimates.

ABSTRACT: The broader autism phenotype (BAP) is a collection of sub-diagnostic autistic traits more common in families of individuals with autism spectrum disorder (ASD) than in the general population. BAP is a latent construct that can be defined using different domains, measured using multiple instruments, and reported using different techniques. Therefore, estimates of BAP may vary greatly across studies. Our objective was to systematically review studies that reported occurrence of BAP in parents of children with ASD in order to quantify and describe heterogeneity in estimates. We systematically searched PubMed and Scopus using PRISMA guidelines for studies quantifying percentage of parents of children with ASD who had BAP We identified 41 studies that measured BAP in parents of children with AS

SUBMITTER: Rubenstein E 

PROVIDER: S-EPMC5933863 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature