Seasonal Incidence of Symptomatic Influenza in the United States.

ABSTRACT:

Background

The seasonal incidence of influenza is often approximated as 5%-20%.

Methods

We used 2 methods to estimate the seasonal incidence of symptomatic influenza in the United States. First, we made a statistical estimate extrapolated from influenza-associated hospitalization rates for 2010-2011 to 2015-2016, collected as part of national surveillance, covering approximately 9% of the United States, and including the existing mix of vaccinated and unvaccinated persons. Second, we performed a literature search and meta-analysis of published manuscripts that followed cohorts of subjects during 1996-2016 to detect laboratory-confirmed symptomatic influenza among unvaccinated persons; we adjusted this result to the US median vaccination coverage and effectiveness during 2010

SUBMITTER: Tokars JI 

PROVIDER: S-EPMC5934309 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature