Prenatal traffic-related air pollution exposures, cord blood adipokines and infant weight.

ABSTRACT:

Objective

Studies suggest that prenatal exposure to traffic-related air pollution (TRAP) may contribute to childhood obesity. While exact mechanisms for this association are unknown, circulating adipokines are hypothesized to contribute to early-life weight gain.

Methods

The Maternal and Child Health Study birth cohort included 136 women from the Los Angeles County + University of Southern California Medical Center. This study estimated prenatal residential TRAP exposure and used linear regression analysis to examine associations between adipokines with TRAP exposure and infant weight change (birth to 6 months).

Results

A one standard deviation (1-SD: 2 ppb) increase in prenatal non-freeway nitrogen oxides was associated with 33% (P = 0.01) higher leptin and 9% higher

SUBMITTER: Alderete TL 

PROVIDER: S-EPMC5934325 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature