Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study.

ABSTRACT: BACKGROUND:The aim was to develop prediction rules that may guide early treatment decisions based on baseline clinical predictors of long-term unfavorable outcome in juvenile idiopathic arthritis (JIA). METHODS:In the Nordic JIA cohort, we assessed baseline disease characteristics as predictors of the following outcomes 8 years after disease onset. Non-achievement of remission off medication according to the preliminary Wallace criteria, functional disability assessed by Childhood Health Assessment Questionnaire (CHAQ) and Physical Summary Score (PhS) of the Child Health Questionnaire, and articular damage assessed by the Juvenile Arthritis Damage Index-Articular (JADI-A). Multivariable models were constructed, and cross-validations were performed by repeated partitioning of the cohort int

SUBMITTER: Rypdal V 

PROVIDER: S-EPMC5934822 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature