Bioprospection of actinobacteria derived from freshwater sediments for their potential to produce antimicrobial compounds.

ABSTRACT:

Background

Actinobacteria from freshwater habitats have been explored less than from other habitats in the search for compounds of pharmaceutical value. This study highlighted the abundance of actinobacteria from freshwater sediments of two rivers and one lake, and the isolates were studied for their ability to produce antimicrobial bioactive compounds.

Results

16S rRNA gene sequencing led to the identification of 84 actinobacterial isolates separated into a common genus (Streptomyces) and eight rare genera (Nocardiopsis, Saccharopolyspora, Rhodococcus, Prauserella, Amycolatopsis, Promicromonospora, Kocuria and Micrococcus). All strains that showed significant inhibition potentials were found against Gram-positive, Gram-negative and yeast pathogens. Further, three biosynthet

SUBMITTER: Zothanpuia 

PROVIDER: S-EPMC5935920 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature