Phylogeny Trumps Chemotaxonomy: A Case Study Involving Turicella otitidis.

ABSTRACT: The genus Turicella was proposed to harbor clinical strains isolated from middle-ear fluids of patients with otitis media. 16S rRNA phylogeny showed that it belonged to the mycolic acid-containing actinobacteria, currently classified in the order Corynebacteriales, and was closely related to the genus Corynebacterium. A new genus was proposed for the organisms as unlike corynebacteria they lacked mycolic acids and had different menaquinones. Here, we carried out large-scale comparative genomics on representative strains of the genera Corynebacterium and Turicella to check if this chemotaxonomic classification is justified. Three genes that are known to play an essential role in mycolic acid biosynthesis were absent in Turicella and two other mycola

SUBMITTER: Baek I 

PROVIDER: S-EPMC5936774 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature