Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online.

ABSTRACT: Systems biology is the study of complex living organisms, and as such, analysis on a systems-wide scale involves the collection of information-dense data sets that are representative of an entire phenotype. To uncover dynamic biological mechanisms, bioinformatics tools have become essential to facilitating data interpretation in large-scale analyses. Global metabolomics is one such method for performing systems biology, as metabolites represent the downstream functional products of ongoing biological processes. We have developed XCMS Online, a platform that enables online metabolomics data processing and interpretation. A systems biology workflow recently implemented within XCMS Online enables rapid metabolic pathway mapping using raw metabolomics data for investigating dysregulated metabo

SUBMITTER: Forsberg EM 

PROVIDER: S-EPMC5937130 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature