Smoking and outcomes in kidney transplant recipients: a post hoc survival analysis of the FAVORIT trial.

ABSTRACT:

Background

Tobacco use remains an international health problem with between 10% and 40% of adults currently using tobacco. Given the rising number of patients either awaiting or having received a kidney transplant and the absence of smoking cessation as the criterion for transplantation in guidelines, we explored the association between smoking status and clinical outcomes in kidney transplant recipients.

Patients and methods

In this post hoc analysis of the Folic Acid for Vascular Outcome Reduction in Transplant trial, the associations between smoking status, defined as never having smoked, formerly or currently smoking, and both all-cause mortality and graft survival were assessed using Cox proportional hazards models. Fatal events were centrally adjudicated into prespecif

SUBMITTER: Weinrauch LA 

PROVIDER: S-EPMC5937486 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature