Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results.

ABSTRACT:

Introduction

The aim was to examine associations between midlife cardiovascular health (CVH) and 20-year cognitive decline among blacks and whites.

Methods

Midlife CVH metrics (American Heart Association's Life's Simple 7) were calculated and examined in relation to midlife and 20-year change in cognitive function among 13,270 whites and blacks from the Atherosclerosis Risk in Communities Cohort Study. We used linear mixed models to estimate adjusted associations of midlife CVH with midlife cognitive status and change.

Results

Higher midlife (Life's Simple 7) scores and individual metrics, particularly blood pressure and glucose, were associated with better midlife cognition and reduced 20-year decline. Midlife CVH 20-year neuroprotection was more pronounced among whi

SUBMITTER: Gonzalez HM 

PROVIDER: S-EPMC5938099 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature