The Cytoarchitecture of Domain-specific Regions in Human High-level Visual Cortex.

ABSTRACT: A fundamental hypothesis in neuroscience proposes that underlying cellular architecture (cytoarchitecture) contributes to the functionality of a brain area. However, this hypothesis has not been tested in human ventral temporal cortex (VTC) that contains domain-specific regions causally involved in perception. To fill this gap in knowledge, we used cortex-based alignment to register functional regions from living participants to cytoarchitectonic areas in ex vivo brains. This novel approach reveals 3 findings. First, there is a consistent relationship between domain-specific regions and cytoarchitectonic areas: each functional region is largely restricted to 1 cytoarchitectonic area. Second, extracting cytoarchitectonic profiles from face- and place-selective regions after back-projecting

SUBMITTER: Weiner KS 

PROVIDER: S-EPMC5939223 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature