Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants.

ABSTRACT:

Objective

To investigate the association of grip strength with disease specific incidence and mortality and whether grip strength enhances the prediction ability of an established office based risk score.

Design

Prospective population based study.

Setting

UK Biobank.

Participants

502 293 participants (54% women) aged 40-69 years.

Main outcome measures

All cause mortality as well as incidence of and mortality from cardiovascular disease, respiratory disease, chronic obstructive pulmonary disease, and cancer (all cancer, colorectal, lung, breast, and prostate).

Results

Of the participants included in analyses, 13 322 (2.7%) died over a mean of 7.1 (range 5.3-9.9) years' follow-up. In women and men, respectively, hazard ratios per 5 kg lower grip str

SUBMITTER: Celis-Morales CA 

PROVIDER: S-EPMC5939721 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature