The fallopian tube microbiome: implications for reproductive health.

ABSTRACT:

Objective

There is a paucity of data characterizing the microbiota of the female upper genital tract, which controversially is described as a sterile site. We examine whether the fallopian tube harbours an endogenous microbial community.

Design

This prospective study collected from women undergoing total hysterectomy or salpingectomy-oophorectomy.

Setting

Private hospital gynaecology department.

Patients

Fallopian tubes were collected from women diagnosed with benign disease or for prophylaxis.

Interventions

Samples were interrogated for the presence of microbial DNA using a next generation sequencing technology approach to exploit the V5 to V9 regions of the 16S rRNA gene.

Main outcome measures

The fallopian tube microbiota was characterized usin

SUBMITTER: Pelzer ES 

PROVIDER: S-EPMC5940370 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature