Population-level decline in BMI and systolic blood pressure following mass HIV treatment: Evidence from rural KwaZulu-Natal.

ABSTRACT:

Objective

Clinic-based studies have shown that patients with human immunodeficiency virus (HIV) gain weight after initiation of antiretroviral therapy (ART). This study aimed to determine whether the scale-up of ART was associated with a population-level increase in body mass index (BMI) and blood pressure (BP) in a community with high HIV and obesity prevalence.

Methods

A household survey was conducted in rural KwaZulu-Natal before ART scale-up (in 2004) and when ART coverage had reached 25% (in 2010). Anthropometric data was linked with HIV surveillance data.

Results

Mean BMI decreased in women from 29.9 to 29.1 kg/m² (P = 0.002) and in men from 24.2 to 23.0 kg/m² (P < 0.001). Similarly, overweight and obesity prevalence declined significantly

SUBMITTER: Geldsetzer P 

PROVIDER: S-EPMC5940485 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature