Ambient PM_2.5 air pollution exposure and hepatocellular carcinoma incidence in the United States.

ABSTRACT:

Purpose

To conduct the first epidemiologic study prospectively examining the association between particulate matter air pollution < 2.5 µm in diameter (PM_2.5) exposure and hepatocellular carcinoma (HCC) risk in the U.S.

Methods

Surveillance, Epidemiology, and End Results (SEER) provided information on HCC cases diagnosed between 2000 and 2014 from 16 population-based cancer registries across the U.S. Ambient PM_2.5 exposure was estimated by linking the SEER county with a spatial PM_2.5 model using a geographic information system. Poisson regression with robust variance estimation was used to calculate incidence rate ratios and 95% confidence intervals (CIs) for the association between ambient PM_2.5 exposure per 10 µg/m³ in

SUBMITTER: VoPham T 

PROVIDER: S-EPMC5940508 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature