Effect of flavoring chemicals on free radical formation in electronic cigarette aerosols.

ABSTRACT:

Background

Flavoring chemicals, or flavorants, have been used in electronic cigarettes (e-cigarettes) since their inception; however, little is known about their toxicological effects. Free radicals present in e-cigarette aerosols have been shown to induce oxidative stress resulting in damage to proliferation, survival, and inflammation pathways in the cell. Aerosols generated from e-liquid solvents alone contain high levels of free radicals but few studies have looked at how these toxins are modulated by flavorants.

Objectives

We investigated the effects of different flavorants on free radical production in e-cigarette aerosols.

Methods

Free radicals generated from 49 commercially available e-liquid flavors were captured and analyzed using electron paramagnetic reson

SUBMITTER: Bitzer ZT 

PROVIDER: S-EPMC5940571 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature