Reproductive stage associated changes in plasma fatty acid profile and proinflammatory cytokine expression in rat mammary glands.

ABSTRACT: Mastitis is a common disease for mammals all around the world. Figuring out why mastitis mainly occurs around parturition may be helpful for dealing with the disease. Lipolytic activity and oxidative stress take place around parturition, which may leads to alteration in fatty acids profile and proinflammatory cytokine expression. Thus, the aim of the present study was to further our understanding about the high incidence of mastitis around parturition by comparison of plasma fatty acid profile and mammary inflammation indicators at different reproductive stages. A total of 47 female rats were included in the present study. After mating, all the pregnant and non-pregnant rats began to receive the same experimental diet. Blood samples were collected at day 1 and 14 of gestation as well as da

SUBMITTER: Lin S 

PROVIDER: S-EPMC5941025 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature