Higher serum 25(OH)D level is associated with decreased risk of impairment of glucose homeostasis: data from Southwest China.

ABSTRACT:

Background

Recent epidemiological studies have suggested inverse associations between vitamin D status and metabolic diseases including type 2 diabetes (T2DM). The aim of this study was to examine whether a higher serum 25-hydroxyvitamin D (25(OH)D) was associated with a more favorable glucose homeostasis among adults without diabetes in Southwest China.

Methods

Serum 25(OH)D concentration was measured in a cross-sectional sample of 1514 adults without diabetes aged 25-65 years recruited from Southwest China. Indices describing glucose homeostasis included fasting plasma glucose (FPG), fasting insulin, glycated hemoglobin (HbA_1c), the homeostatic model assessment 2-insulin resistance (HOMA2-IR) and odds of pre-diabetes. Data were analyzed by multivariable-adjusted

SUBMITTER: Li D 

PROVIDER: S-EPMC5941481 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature