Endovascular Baroreflex Amplification for Resistant Hypertension.

ABSTRACT:

Purpose of review

Most hypertension devices have been designed to interrupt or modify the sympathetic nervous system, which seems to be unbalanced in hypertension. Carotid baroreceptors play a pivotal role in maintaining adrenergic balance via a direct feedback interface and would be an exceptional target for intervention. The purpose of this review is to define the role of the baroreceptor in hypertension, to examine device-based therapies targeting the baroreflex and to explore future promises of endovascular baroreflex amplification (EBA).

Recent findings

In the last two decades, two therapeutic strategies targeting the carotid baroreceptor have evolved: baroreflex activation therapy (BAT) and EBA. Both therapies enhance baroreceptor activity, either directly by electrica

SUBMITTER: van Kleef MEAM 

PROVIDER: S-EPMC5942348 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature