Long-Run Trends in Antidepressant Use Among Youths After the FDA Black Box Warning.

ABSTRACT:

Objective

In October 2004, the Food and Drug Administration directed pharmaceutical companies to issue a black box warning about the potential link between the use of antidepressants and suicidal ideation among children. This study analyzed long-run trends in antidepressant use among children before and after the black box warning for those with and without severe psychological impairment.

Methods

The analysis used data from the Medical Expenditure Panel Survey for children ages five to 17, covering years 2000-2011 (N=75,819). The study used multivariate probit models to compare the changes in the rate of any antidepressant use in the early (2004-2007) and late (2008-2011) postwarning years with the rate in the prewarning years (2002-2003). Recycled predictions methods were

SUBMITTER: Kafali N 

PROVIDER: S-EPMC5942898 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature