Electron Transfer Dissociation and Collision-Induced Dissociation of Underivatized Metallated Oligosaccharides.

ABSTRACT: Electron transfer dissociation (ETD) and collision-induced dissociation (CID) were used to investigate underivatized, metal-cationized oligosaccharides formed via electrospray ionization (ESI). Reducing and non-reducing sugars were studied including the tetrasaccharides maltotetraose, 3α,4β,3α-galactotetraose, stachyose, nystose, and a heptasaccharide, maltoheptaose. Univalent alkali, divalent alkaline earth, divalent and trivalent transition metal ions, and a boron group trivalent metal ion were adducted to the non-permethylated oligosaccharides. ESI generated [M + Met]⁺, [M + 2Met]²⁺, [M + Met]²⁺, [M + Met - H]⁺, and [M + Met - 2H]⁺ most intensely along with low intensity nitrate adducts, depending on the metal and sugar ionized. The

SUBMITTER: Schaller-Duke RM 

PROVIDER: S-EPMC5943087 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature