Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease.

ABSTRACT:

Introduction

Identification of factors associated with progression of cognitive symptoms in Parkinson's disease (PD) is important for treatment planning, clinical care, and design of future clinical trials. The current study sought to identify whether prediction of cognitive progression is aided by examining baseline cognitive features, and whether this differs according to stage of cognitive disease.

Methods

Participants with PD in the Pacific Udall Center Clinical Consortium who had longitudinal data available and were nondemented at baseline were included in the study (n = 418). Logistic and Cox regression models were utilized to examine the relationship between cognitive, demographic, and clinical variables with risk and time to progression from no cognitive impairment t

SUBMITTER: Cholerton B 

PROVIDER: S-EPMC5943177 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature