Quantification of FDG-PET/CT with delayed imaging in patients with newly diagnosed recurrent breast cancer.

ABSTRACT:

Background

Several studies have shown the advantage of delayed-time-point imaging with 18F-FDG-PET/CT to distinguish malignant from benign uptake. This may be relevant in cancer diseases with low metabolism, such as breast cancer. We aimed at examining the change in SUV from 1 h (1h) to 3 h (3h) time-point imaging in local and distant lesions in patients with recurrent breast cancer. Furthermore, we investigated the effect of partial volume correction in the different types of metastases, using semi-automatic quantitative software (ROVER™).

Methods

One-hundred and two patients with suspected breast cancer recurrence underwent whole-body PET/CT scans 1h and 3h after FDG injection. Semi-quantitative standardised uptake values (SUVmax, SUVmean) and partial volume corrected SUVm

SUBMITTER: Baun C 

PROVIDER: S-EPMC5943993 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature