Association of the APOA1 rs964184 SNP and serum lipid traits in the Chinese Maonan and Han populations.

ABSTRACT:

Background

Maonan nationality belongs to a mountain ethnic minority in China. Little is known about the association of apolipoprotein A1 gene (APOA1) rs964184 single nucleotide polymorphism (SNP) and serum lipid levels in this population. The aim of this study was to detect the association of the APOA1 rs964184 SNP and several environmental factors with serum lipid profiles in the Chinese Maonan and Han populations.

Methods

Genotypes of the APOA1 rs964184 SNP in 867 individuals of Maonan nationality and 820 participants of Han nationality were determined by polymerase chain reaction and restriction fragment length polymorphism, combined with gel electrophoresis, and confirmed by direct sequencing.

Results

The frequencies of CC, CG and GG genotypes of the APOA1 rs96418

SUBMITTER: Qiu L 

PROVIDER: S-EPMC5944063 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature