Arterial stiffness in adults with steady-state bronchiectasis: association with clinical indices and disease severity.

ABSTRACT:

Background

Cardiovascular disease are common co-morbidities in bronchiectasis and contribute substantially to disease burden and mortality. Brachial-ankle pulse wave velocity (baPWV), a measure of arterial stiffness, has a strong predictive value for cardiovascular event. We hypothesized that baPWV would be increased in steady-state bronchiectasis patients, and correlates with the degree of systemic inflammation and disease severity assessed with Bronchiectasis Severity Index and FACED scores.

Methods

Eighty patients with steady-state bronchiectasis and 80 age- and sex-matched controls were enrolled. BaPWV was measured as an indicator of arterial stiffness. Demographic, clinical indices, radiology, spirometry, sputum bacteriology and systemic inflammatory mediators were also

SUBMITTER: Gao YH 

PROVIDER: S-EPMC5944117 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature