In-vivo optical imaging in head and neck oncology: basic principles, clinical applications and future directions.

ABSTRACT: Head and neck cancers become a severe threat to human's health nowadays and represent the sixth most common cancer worldwide. Surgery remains the first-line choice for head and neck cancer patients. Limited resectable tissue mass and complicated anatomy structures in the head and neck region put the surgeons in a dilemma between the extensive resection and a better quality of life for the patients. Early diagnosis and treatment of the pre-malignancies, as well as real-time in vivo detection of surgical margins during en bloc resection, could be leveraged to minimize the resection of normal tissues. With the understanding of the head and neck oncology, recent advances in optical hardware and reagents have provided unique opportunities for real-time pre-malignancies and cancer imaging in the

SUBMITTER: Wu C 

PROVIDER: S-EPMC5944254 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature