Association between ERα gene Pvu II polymorphism and breast cancer susceptibility: A meta-analysis.

ABSTRACT:

Background

Estrogen has played an important role in the development of breast cancer. ER-α PvuII gene polymorphism is in close association with the occurrence risk of breast cancer, but no consensus has been achieved currently.

Methods

PubMed, Embase, China National Knowledge Infrastructure (CNKI) database, Wanfang database, and VIP database were retrieved to collect the case-control studies on association between ERα gene Pvu II polymorphism and breast cancer risk published before September 1, 2017. Newcastle-Ottawa Scale (NOS) was used to assess the quality of the literatures, Stata 14.0 software was applied for meta-analysis, and the pooled odds ratio (OR) and 95% confidence interval (95% CI) were calculated. The subgroup analysis was performed to assess the confounding f

SUBMITTER: Zhang ZL 

PROVIDER: S-EPMC5944501 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature