Evaluating verbal learning and memory in patients with an at-risk mental state or first episode psychosis using structural equation modelling.

ABSTRACT:

Background

Verbal learning and memory are impaired not only in patients with a first episode of psychosis (FEP) but also-to a lower extent-in those with an at-risk mental state for psychosis (ARMS). However, little is known about the specific nature of these impairments. Hence, we aimed to study learning and memory processes in ARMS and FEP patients by making use of structural equation modelling.

Methods

Verbal learning was assessed with the California Verbal Learning Test (CVLT) in 98 FEP patients, 126 ARMS patients and 68 healthy controls (HC) as part of the Basel early detection of psychosis (FePsy) study. The four-factorial CFA model of Donders was used to estimate test performance on latent variables of the CVLT and growth curve analysis was used to model the learning c

SUBMITTER: Egloff L 

PROVIDER: S-EPMC5944996 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature