Association between perfluoroalkyl substances exposure and thyroid function in adults: A meta-analysis.

ABSTRACT:

Objective

Many people are exposed to perfluoroalkyl substances (PFASs) because these substances are widely used as industrial products. Although epidemiological studies suggest that PFASs can disrupt thyroid hormones, the association between PFAS exposure and thyroid function remains inconclusive. Therefore, we performed a comprehensive meta-analysis to investigate the association between PFASs exposure and thyroid hormones.

Methods

We searched medical literature databases for articles on the association between PFASs-perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorohexane sulfonic acid (PFHxS)-and thyroid hormone levels in adults. Twelve articles were included in the meta-analysis, and the pooled z values were calculated with correlation or r

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC5945046 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature