Biomarkers as Common Data Elements for Symptom and Self-Management Science.

ABSTRACT:

Purpose

Biomarkers as common data elements (CDEs) are important for the characterization of biobehavioral symptoms given that once a biologic moderator or mediator is identified, biologically based strategies can be investigated for treatment efforts. Just as a symptom inventory reflects a symptom experience, a biomarker is an indicator of the symptom, though not the symptom per se. The purposes of this position paper are to (a) identify a "minimum set" of biomarkers for consideration as CDEs in symptom and self-management science, specifically biochemical biomarkers; (b) evaluate the benefits and limitations of such a limited array of biomarkers with implications for symptom science; (c) propose a strategy for the collection of the endorsed minimum set of biologic samples to be em

SUBMITTER: Page GG 

PROVIDER: S-EPMC5945303 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature