Whole genome sequence and phenotypic characterization of a Cbm⁺ serotype e strain of Streptococcus mutans.

ABSTRACT: We report the whole genome sequence of the serotype e Cbm⁺ strain LAR01 of Streptococcus mutans, a dental pathogen frequently associated with extra-oral infections. The LAR01 genome is a single circular chromosome of 2.1 Mb with a GC content of 36.96%. The genome contains 15 phosphotransferase system gene clusters, seven cell wall-anchored (LPxTG) proteins, all genes required for the development of natural competence and genes coding for mutacins VI and K8. Interestingly, the cbm gene is genetically linked to a putative type VII secretion system that has been found in Mycobacteria and few other Gram-positive bacteria. When compared with the UA159 type strain, phenotypic characterization of LAR01 revealed increased biofilm formation in the presence of either glucose or sucrose bu

SUBMITTER: Aviles-Reyes A 

PROVIDER: S-EPMC5945312 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature