Global evolution and phylogeography of Brucella melitensis strains.

ABSTRACT:

Background

Brucellosis is a bacterial zoonotic disease. Annually in the world more than 500,000 new cases of brucellosis in humans are registered. In this study, we propose an evolutionary model of the historical distribution of B. melitensis based on the full-genomic SNP analysis of 98 strains.

Results

We performed an analysis of the SNP of the complete genomes of 98 B. melitensis strains isolated in different geographical regions of the world to obtain relevant information on the population structure, genetic diversity and the evolution history of the species. Using genomic sequences of 21 strains of B. melitensis isolated in Russia and WGS data from the NCBI database, it was possible to identify five main genotypes and 13 species genotypes for analysis. Data analysis base

SUBMITTER: Pisarenko SV 

PROVIDER: S-EPMC5946514 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature