Randomized controlled trial of a home-based palliative approach for people with severe multiple sclerosis.

ABSTRACT:

Background

Evidence on the efficacy of palliative care in persons with severe multiple sclerosis (MS) is scarce.

Objective

To assess the efficacy of a home-based palliative approach (HPA) for adults with severe MS and their carers.

Methods

Adults with severe MS-carer dyads were assigned (2:1 ratio) to either HPA or usual care (UC). At each center, a multi-professional team delivered the 6-month intervention. A blind examiner assessed dyads at baseline, 3 months, and 6 months. Primary outcome measures were Palliative care Outcome Scale-Symptoms-MS (POS-S-MS) and Schedule for the Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW, not assessed in severely cognitively compromised patients).

Results

Of 78 dyads randomized, 76 (50 HPA, 26 UC) were

SUBMITTER: Solari A 

PROVIDER: S-EPMC5946675 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature