Crystal structures of two new 3-(2-chloro-eth-yl)-r(2),c(6)-diarylpiperidin-4-ones.

ABSTRACT: The syntheses and crystal structures of 3-(2-chloro-eth-yl)-r-2,c-6-di-phenyl-piperidin-4-one, C₁₉H₂₀ClNO, (I), and 3-(2-chloro-eth-yl)-r-2,c-6-bis-(4-fluoro-phen-yl)piperidin-4-one, C₁₉H₁₈ClF₂NO, (II), are described. The piperidone ring adopts a chair conformation in (I), whereas a slightly distorted chair conformation is formed in (II). The dihedral angle between the mean plane of the phenyl rings is 59.1 (1)° in (I) and 76.1 (1)° in (II). The crystal packing features weak inter-molecular N-H⋯O hydrogen bonds in each structure.

SUBMITTER: Rajkumar K 

PROVIDER: S-EPMC5946973 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature