Effects of the source gap on transmission efficiency of a quadrupole mass spectrometer.

ABSTRACT:

Rationale

Recent trends towards miniature and portable quadrupole mass spectrometry (QMS) entail challenges in instrumental sensitivity, which is influenced by 3D fringe field effects on ion transmission in the Quadrupole Mass Filter (QMF). The relationship of these effects with the gap from the ion source to the QMF entrance (source gap) is significant and little explored. We examine transmission characteristics experimentally and use the results to test the predictive accuracy of a recently developed 3D QMF simulation model. The model is then applied to directly investigate optimal transmission m/z ranges across multiple source gaps.

Methods

A portable single filter quadrupole mass spectrometer is used to analyse transmission characteristics across a range of common gases.

SUBMITTER: Antony Joseph MJ 

PROVIDER: S-EPMC5947150 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature