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Autologous Stem Cell Transplantation in Elderly Lymphoma Patients in Their 70s: Outcomes and Analysis.


ABSTRACT:

Background

High-dose chemotherapy and autologous stem cell transplantation (ASCT) can offer durable remission in many patients with relapsed or high-risk lymphoma. However, elderly patients are often not considered ASCT candidates based on age alone.

Subjects, materials, and methods

A retrospective analysis of patients ≥70 years of age with a diagnosis of Hodgkin or non-Hodgkin lymphoma receiving ASCT between 2000 and 2016 at two partner institutions was performed. Clinical data were extracted from institutional databases and individual medical records. Multivariate analysis was performed to examine the association of clinical variables with transplant outcomes.

Results

One hundred seven patients were identified. Median age at transplant was 72 years (range, 70-79). T

SUBMITTER: Sun L 

PROVIDER: S-EPMC5947447 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature