Trends and uptake of new formulations of controlled-release oxycodone in Canada.

ABSTRACT:

Purpose

This study investigated the impact of changing availability of tamper-deterrent and non-tamper-deterrent oxycodone on prescribing patterns of controlled-release oxycodone across Canada.

Methods

We conducted a population-based, serial cross-sectional study of controlled-release oxycodone dispensing from community pharmacies across Canada between October 2007 and April 2016. We calculated rates of dispensing (tablets per 100 population) and reported the relative market share of generic non-tamper-deterrent controlled-release oxycodone. All analyses were reported nationally and stratified by province.

Results

After the introduction of a tamper-deterrent formulation, the national rate of controlled-release oxycodone dispensing fell by 44.6% (from 26.4 to 14.6 tabl

SUBMITTER: Gomes T 

PROVIDER: S-EPMC5947657 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature