Clinical correlates of augmentation/combination treatment strategies in major depressive disorder.

ABSTRACT:

Objective

This multicenter, multinational, cross-sectional study aimed to investigate clinical characteristics and treatment outcomes associated with augmentation/combination treatment strategies in major depressive disorder (MDD).

Method

Sociodemographic, clinical, and treatment features of 1410 adult MDD patients were compared between MDD patients treated with monotherapy and augmentation/combination medication using descriptive statistics, analyses of covariance (ancova), and Spearman's correlation analyses.

Results

60.64% of all participants received augmentation and/or combination strategies with a mean number of 2.18 ± 1.22 simultaneously prescribed psychiatric drugs. We found male gender, older age, Caucasian descent, higher weight, low educational status, abse

SUBMITTER: Dold M 

PROVIDER: S-EPMC5947736 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature