Fecal microbiome of periparturient dairy cattle and associations with the onset of Salmonella shedding.

ABSTRACT: Non-typhoidal Salmonella enterica is a zoonotic pathogen with critical importance in animal and public health. The persistence of Salmonella on farms affects animal productivity and health, and represents a risk for food safety. The intestinal microbiota plays a fundamental role in the colonization and invasion of this ubiquitous microorganism. To overcome the colonization resistance imparted by the gut microbiome, Salmonella uses invasion strategies and the host inflammatory response to survive, proliferate, and establish infections with diverse clinical manifestations. Cattle serve as reservoirs of Salmonella, and periparturient cows have high prevalence of Salmonella shedding; however, little is known about the association between the gut microbiome and the onset of Salmonella shedding

SUBMITTER: Munoz-Vargas L 

PROVIDER: S-EPMC5947886 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature