Early-Life Selenium Status and Cognitive Function at 5 and 10 Years of Age in Bangladeshi Children.

ABSTRACT:

Background

In older adults, selenium status has been positively associated with cognitive function. We recently reported a positive association between maternal selenium status in pregnancy and children's cognitive function at 1.5 y.

Objective

We followed up the children to assess if prenatal and childhood selenium status was associated with cognitive abilities at 5 and 10 y.

Methods

This longitudinal cohort study was nested in Maternal and Infant Nutrition Interventions in Matlab (MINIMat), a population-based, randomized supplementation trial in pregnancy in rural Bangladesh. Selenium in maternal blood [erythrocyte fraction (Ery-Se) at baseline] and in child hair and urine was measured using inductively coupled plasma mass spectrometry. Children's cognition at 5 and

SUBMITTER: Skroder H 

PROVIDER: S-EPMC5947942 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature