Utility of inverse probability weighting in molecular pathological epidemiology.

ABSTRACT: As one of causal inference methodologies, the inverse probability weighting (IPW) method has been utilized to address confounding and account for missing data when subjects with missing data cannot be included in a primary analysis. The transdisciplinary field of molecular pathological epidemiology (MPE) integrates molecular pathological and epidemiological methods, and takes advantages of improved understanding of pathogenesis to generate stronger biological evidence of causality and optimize strategies for precision medicine and prevention. Disease subtyping based on biomarker analysis of biospecimens is essential in MPE research. However, there are nearly always cases that lack subtype information due to the unavailability or insufficiency of biospecimens. To address this missing subtyp

SUBMITTER: Liu L 

PROVIDER: S-EPMC5948129 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature