Combining population genomics and fitness QTLs to identify the genetics of local adaptation in Arabidopsis thaliana.

ABSTRACT: Evidence for adaptation to different climates in the model species Arabidopsis thaliana is seen in reciprocal transplant experiments, but the genetic basis of this adaptation remains poorly understood. Field-based quantitative trait locus (QTL) studies provide direct but low-resolution evidence for the genetic basis of local adaptation. Using high-resolution population genomic approaches, we examine local adaptation along previously identified genetic trade-off (GT) and conditionally neutral (CN) QTLs for fitness between locally adapted Italian and Swedish A. thaliana populations [Ågren J, et al. (2013) Proc Natl Acad Sci USA 110:21077-21082]. We find that genomic regions enriched in high F_ST SNPs colocalize with GT QTL peaks. Many of these hig

SUBMITTER: Price N 

PROVIDER: S-EPMC5948977 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature