Gender Differences in Axial Spondyloarthritis: Women Are Not So Lucky.

ABSTRACT: PURPOSE OF REVIEW:Ankylosing spondylitis (AS) was historically seen as a predominantly male disease. However, more recent data showed a more homogenous sex prevalence. Unfortunately, in many studies in axial spondyloarthritis (axSpA), the number of women included is low and the analyses are often not stratified for gender distribution. The purpose of this review is to aggregate the existing data on gender differences in axSpA in order to increase the awareness that female axSpA patients are still under-recognized. RECENT FINDINGS:Several studies considering gender differences revealed that female axSpA patients had different disease manifestations due to different immunological, hormonal, and genetic responses. For instance, allelic frequencies of the AHNK-gene and tissue non-specific alka

SUBMITTER: Rusman T 

PROVIDER: S-EPMC5949138 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature