Myocardial performance index in hypertensive disorders of pregnancy: The relationship between blood pressures and angiogenic factors.

ABSTRACT:

Objective

To study the association between cardiac function measured by myocardial performance index (MPI), blood pressures and angiogenic factors measured at the time of echocardiography in patients with and without hypertensive disorders of pregnancy (HDP).

Methods

We prospectively studied 189 pregnant women and evaluated whether changes in cardiac function observed on echocardiography were correlated with higher blood pressures and whether higher blood pressures were associated with antiangiogenic proteins (soluble fms-like tyrosine kinase, sFlt1; soluble endoglin, sEng). Comprehensive echocardiograms, including measurement of MPI, were performed on all patients. sFlt1 and sEng levels were measured using enzyme-linked immunosorbent assay.

Results

Overall, 189 patie

SUBMITTER: Ramadan H 

PROVIDER: S-EPMC5949867 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature