The Rome IV versus Rome III criteria for heartburn diagnosis: A comparative study.

ABSTRACT:

Background

The phenotypes of heartburn patients are heterogeneous.

Objective

The objective of this study was to investigate the proportion of heartburn phenotypes in a Chinese population and to compare the Rome IV and III criteria for heartburn diagnosis.

Methods

A retrospective study was performed among heartburn patients referred for upper endoscopy and esophageal function tests in a tertiary hospital. Their symptoms fulfilled Rome IV and III criteria.

Results

A total of 233 patients were included. Fifty-nine patients (25%) were diagnosed with esophagitis, 96 (41%) with non-erosive reflux disease (NERD) and 78 (34%) with functional heartburn (FH) based on Rome III criteria. Approximately 70% of the Rome III NERD patients were changed based on Rome IV criteria

SUBMITTER: Zhang M 

PROVIDER: S-EPMC5949975 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature