Unknown

Dataset Information

0

The dynamic life of the glycogen granule.


ABSTRACT: Glycogen, the primary storage form of glucose, is a rapid and accessible form of energy that can be supplied to tissues on demand. Each glycogen granule, or "glycosome," is considered an independent metabolic unit composed of a highly branched polysaccharide and various proteins involved in its metabolism. In this Minireview, we review the literature to follow the dynamic life of a glycogen granule in a multicompartmentalized system, i.e. the cell, and how and where glycogen granules appear and the factors governing its degradation. A better understanding of the importance of cellular compartmentalization as a regulator of glycogen metabolism is needed to unravel its role in brain energetics.

SUBMITTER: Prats C 

PROVIDER: S-EPMC5949993 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

altmetric image

Publications

The dynamic life of the glycogen granule.

Prats Clara C   Graham Terry E TE   Shearer Jane J  

The Journal of biological chemistry 20180226 19


Glycogen, the primary storage form of glucose, is a rapid and accessible form of energy that can be supplied to tissues on demand. Each glycogen granule, or "glycosome," is considered an independent metabolic unit composed of a highly branched polysaccharide and various proteins involved in its metabolism. In this Minireview, we review the literature to follow the dynamic life of a glycogen granule in a multicompartmentalized system, <i>i.e.</i> the cell, and how and where glycogen granules appe  ...[more]

Similar Datasets

| S-EPMC10198547 | biostudies-literature
| S-EPMC3697948 | biostudies-literature
| S-EPMC2920663 | biostudies-literature
| S-EPMC7719152 | biostudies-literature
| S-EPMC8064753 | biostudies-literature
| S-EPMC5662024 | biostudies-literature
| S-EPMC8516698 | biostudies-literature
| S-EPMC6333882 | biostudies-literature
| S-EPMC8844045 | biostudies-literature
| S-EPMC8414849 | biostudies-literature